Circular Dichroism of DNA

Circular dichroism and conformational polymorphism of DNA

Here we review studies that provided important information about conformational properties of DNA using circular dichroic (CD) spectroscopy. The conformational properties include the B-family of structures, A-form, Z-form, guanine quadruplexes, cytosine quadruplexes, triplexes and other less characterized structures. CD spectroscopy is extremely sensitive and relatively inexpensive. This fast a...

Circular dichroism and DNA secondary structure.

The change in average rotation of the DNA helix has been determined for the transfer from 0.05 M NaCl to 3.0 M CsCl, 6.2 M LiCl and 5.4 M NH4Cl. This work, combined with data at lower salt from other laboratories, allows us to relate the intensity of the CD of DNA at 275 nm directly to the change in the number of base pairs per turn. The change in secondary structure for the transfer of DNA fro...

Circular Dichroism of Protein

Toroidal Circular Dichroism

T. A. Raybould,1, ⇤ V. A. Fedotov,1 N. Papasimakis,1 I. Kuprov,2 I. J. Youngs,3 W. T. Chen,4, † D. P. Tsai,4, 5 and N. I. Zheludev1, 6 Optoelectronics Research Centre, University of Southampton, SO17 1BJ, United Kingdom School of Chemistry, University of Southampton, SO17 1BJ, United Kingdom DSTL, Salisbury, United Kingdom Department of Physics, National Taiwan University, Taipei, 10617, Taiwan...

Circular dichroism: electronic

First-principles calculations of electronic circular dichroism (ECD) are widely used to determine absolute configurations of chiral molecules. In addition, ECD is a sensitive probe for the three-dimensional molecular structure, making ECD calculations a useful tool to study conformational changes. In this review, we explain the origin of ECD and optical activity using response theory. While the...